| Daughter | Alice Sprague |
| Son | Edward Sprague |
| Son | Christopher Sprague |
| Son | Ralph Sprague (b. 1603) |
| Son | William Sprague+ (b. 1609, d. 26 October 1675) |
| Marriage | about 1597 | Edward Sprague and Christiana [--?--] were married about 1597. |
| Death | 1614 | He died in 1614. |
| Last Edited | 20 June 2017 |